Mengekstrak Senyawa Bioaktif yang Terkandung pada Kulit Kayu Manis dan Mengidentifikasinya dengan Teknik Gas Chromatography – Mass Spectroscopy (GC-MS)
Abstract
The bioactive compounds contained in cinnamon bark have been extracted. Extraction carried out using ethanol, methanol and water as solvents. The type of compound extracted identified by gas chromatography - mass spectroscopy (GC-MS) technique. From result the identification carried out, obtained as many as eight types of compounds, namely: using ethanol as solvent: (1) cinnamaldehyde, (2) bornylester of acrylic acid, (3) alpha-copaene, (4)Cumarine, and (5) methyl isoheptadecanoate; generated with using methanol as solvent: (6) trioctanoin and (7) 1-hydroxy-2,2-dimethyldecane; and that produced using water as a solvent is (8) 2,5-cyclooctadienol. of the eight Of these compounds, the most dominant is cinnamaldehyde. This shows that the bark Sweet has the main content, cinnamaldehyde. Because the main content is cinnamaldehyde, then cinnamon bark has the potential to be developed in the future as an ingredient herbs for, among others, as anti-diabetic and anti-viral therapy, due to cinnamaldehyde has the character of being able to lower blood sugar levels and is very attractive to weaken the virus. Keywords: Extract, bioactive compounds, cinnamon bark, Gas Chromatography, Mass Spectroscopy.
References
El-Bassossy H.M., Fahmy A., dan Badawy D., (2011). Cinnamaldehyde protects from the hypertension associated with diabetes. Food and Chemical Toxicology, Vol. 49, Hal. 3007–3012.
Kulkarni S.A., Nagarajan S.K., Ramesh V., Palaniyandi V., Selvam S.P., dan Madhavan T., (2020). Computational evaluation of major components from plant essential oils as potent inhibitors of SARS-CoV-2 spike protein. Journal of Molecular Structure, Vol. 1221, No.5 (128823).
Kumar S, Vasudeva N, dan Sharma S., (2012). GC-MS analysis and screening of antidiabetic, antioxidant and hypolipidemic potential of cinnamomum tamala oil in streptozotocin induced diabetes mellitus in rats. Cardiovascular Diabetology, Vol. 11, No. 95, Hal. 1-11.
Pourghanbari G., Nili H., Moattari A., Mohammadi A., dan Iraji A., (2016). Antiviral activity of the oseltamivir and Melissa officinalis L essential oil against avian influenza A virus (H9N2). Virusdisease, Vol. 27, No. 2. Hal. 170-178.
Saad N.Y., Muller C.D., dan Lobstein A., (2013). Major bioactivities and mechanism of action of essential oils and their components. Flavour and Fragrance Journal, Vol. 28, No. 5, Hal. 269-279.
Sadeghi S., Davoodvandi A., Pourhanifeh M.H., Sharifi N., Nezhad R.A., Sahebnasagh R., Moghadam S.A., Sahebkar A., dan Mirzaei H., (2019). Anti-cancer effects of cinnamon: Insights into its apoptosis effects. European Journal of Medicinal Chemistry, Vol. 178, Hal. 131-140.
Schink A., Naumoska K., Kitanovski Z., Kampf C.J., Nowoisky J.F., Thines E., Pöschl U., Schuppan D., dan Lucas K., (2018). Anti-inflammatory effects of cinnamon extract and identification of active compounds influencing the TLR2 and TLR4 signaling pathways. Food & Function, Vol. 9, Hal. 5950–5964.
Tariq S., Wani S., Rasool W., Shafi K., Bhat M.A., Prabhakar A., dan Rather M.A., (2019). A comprehensive review of the antibacterial, antifungal and antiviral potential of essential oils and their chemical constituents against drug-resistant microbial pathogens. Microb. Pathog. Vol. 134 (103580).
Yanakiev S., (2020). Effects of Cinnamon (Cinnamomum spp.) in Dentistry: A Review. Molecules, Vol. 25, Hal. 4184 (1-17).
Zare R., Nadjarzadeh A., Zarshenas M.M., Shams M., dan Heydarig M., (2019). Efficacy of cinnamon in patients with type II diabetes mellitus: A randomized controlled clinical trial. Clinical Nutrition, Vol. 38, Issue 2, Hal. 549-556.
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